Prevalence and echocardiographic predictors of atrial fibrillation in patients with heart failure with preserved ejection fraction
https://doi.org/10.15829/1728-8800-2016-1-20-25
Abstract
Aim. To study the occurrence of atrial fibrillation (AF) in patients with
normal ejection fraction heart failure (NEJHF) without AF in anamnesis,
and to perform comparative analysis of echocardiographic parameters
with the parameters of patients with NEJHF and known AF, as to study
independent predictors of AF occurrence in NEJHF.
Material and methods. Totally, 182 patients included (105 women)
with metabolic syndrome and NEJHF (II-III functional classes by NYHA)
at the age 63±12 y. o., with sinus rhythm and no anamnesis of AF
(n=118), and with paroxysmal AF (PxAF) in anamnesis (n=28) or
persistent (PeAF) in anamnesis (n=36).
Results. Among 118 patients with AF in anamnesis, in 49 (41,5%)
during 3 years of follow-up, there were cases of PeAF and PxAF.
Patients without AF in anamnesis had better relations for left and right
ventricles filling comparison (E/e`) under load, index of maximum left
atrium volume (LA) (IVLAmax), systolic pressure in pulmonary artery
(SPPA) during rest and after exertion, than patients with known
episodes of PeAF and PxAF. Patients with PeAF had significantly higher
values of the index of post systolic shortening of the left ventricle,
rigidity index of LA, IVLAmax, E/e` of RV, interatrial mechanical
asynchrony and low values of longitudinal deformation of the LA (LDLA)
and velocity parameters of LDLA (VPLDLA). Female sex, systolic
arterial pressure, SPPA, IVLAmax, E/e` in load, E/e` of RV, LDLA,
longitudinal deformation of the left ventricle and VPLDLA were
independent predictors of AF.
Conclusion. Increased rigidity, parameters of longitudinal deformation
and the volume of LA, as interatrial mechanical asynchrony are strong
independent predictors of AF in NEJHF.
normal ejection fraction heart failure (NEJHF) without AF in anamnesis,
and to perform comparative analysis of echocardiographic parameters
with the parameters of patients with NEJHF and known AF, as to study
independent predictors of AF occurrence in NEJHF.
Material and methods. Totally, 182 patients included (105 women)
with metabolic syndrome and NEJHF (II-III functional classes by NYHA)
at the age 63±12 y. o., with sinus rhythm and no anamnesis of AF
(n=118), and with paroxysmal AF (PxAF) in anamnesis (n=28) or
persistent (PeAF) in anamnesis (n=36).
Results. Among 118 patients with AF in anamnesis, in 49 (41,5%)
during 3 years of follow-up, there were cases of PeAF and PxAF.
Patients without AF in anamnesis had better relations for left and right
ventricles filling comparison (E/e`) under load, index of maximum left
atrium volume (LA) (IVLAmax), systolic pressure in pulmonary artery
(SPPA) during rest and after exertion, than patients with known
episodes of PeAF and PxAF. Patients with PeAF had significantly higher
values of the index of post systolic shortening of the left ventricle,
rigidity index of LA, IVLAmax, E/e` of RV, interatrial mechanical
asynchrony and low values of longitudinal deformation of the LA (LDLA)
and velocity parameters of LDLA (VPLDLA). Female sex, systolic
arterial pressure, SPPA, IVLAmax, E/e` in load, E/e` of RV, LDLA,
longitudinal deformation of the left ventricle and VPLDLA were
independent predictors of AF.
Conclusion. Increased rigidity, parameters of longitudinal deformation
and the volume of LA, as interatrial mechanical asynchrony are strong
independent predictors of AF in NEJHF.
About the Authors
K. G. Adamyan
SRI of Cardiology. Erevan, Armenia
Armenia
Armenia
L. G. Tunyan
SRI of Cardiology. Erevan, Armenia
Armenia
Armenia
A. L. Chilingaryan
SRI of Cardiology. Erevan, Armenia
Armenia
Armenia
L. R. Tumasyan
SRI of Cardiology. Erevan, Armenia
Armenia
Armenia
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Review
For citations:
Adamyan K.G., Tunyan L.G., Chilingaryan A.L., Tumasyan L.R. Prevalence and echocardiographic predictors of atrial fibrillation in patients with heart failure with preserved ejection fraction. Cardiovascular Therapy and Prevention. 2016;15(1):20-25. (In Russ.) https://doi.org/10.15829/1728-8800-2016-1-20-25
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