Dyslipidemia in the Russian Federation: population data, associations with risk factors
https://doi.org/10.15829/1728-8800-2023-3791
EDN: DGYJLA
Abstract
Aim. To study the prevalence of dyslipidemias and their association with various risk factors in the Russian population of men and women aged 35-74 years in 2020-2022.
Material and methods. This work was carried out as part of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation-3 (ESSE-RF3) study. The sample included 28731 men and women aged 35-74 years living in 15 Russian regions. Hypercholesterolemia (HC) was diagnosed with total cholesterol (TC) ≥5,0 mmol/l, while elevated low-density lipoprotein cholesterol (LDL-C) was considered ≥3,0 mmol/l, hypertriglyceridemia — with triglyceride levels ≥1,7 mmol/l, reduced high-density lipoprotein cholesterol (HDL-C) <1,0 mmol/l in men and <1,2 mmol/l in women. Associations were assessed using logistic regression after adjustment for socio-demographic characteristics, drinking status, presence of hypertension (HTN) and stroke.
Results. The prevalence of hypertriglyceridemia in the Russian Federation in 2020-2022 was 58,8%, hypertriglyceridemia — 32,2%. The incidence of lipid-lowering therapy increased with age from 1% in the group of 35-44 years to 16% in the group of 65-74 years. On average, only 7,6% of study participants received lipid-lowering therapy. Significant associations of HC with HTN, obesity and alcohol abuse were identified. Similar results were obtained for elevated LDL-C levels, with the exception of alcohol abuse. In turn, a reduced HDL-C level was significantly associated with the lack of higher education, marriage, physical activity, smoking and the presence of diseases.
Conclusion. The prevalence of lipid disorders in the Russian Federation in 2020-2022 remained at a high level. These disorders occurred more often in women, and they were better informed about their cholesterol levels and more often received lipid-lowering therapy. HTN, obesity, and some behavioral and social risk factors were associated with dyslipidemia.
About the Authors
O. M. DrapkinaRussian Federation
Moscow
A. E. Imaeva
Russian Federation
Moscow
V. A. Kutsenko
Russian Federation
Moscow
A. V. Kapustina
Russian Federation
Moscow
Yu. A. Balanova
Russian Federation
Moscow
S. A. Maksimov
Russian Federation
Moscow
G. A. Muromtseva
Russian Federation
Moscow
M. B. Kotova
Russian Federation
Moscow
N. S. Karamnova
Russian Federation
Moscow
S. E. Evstifeeva
Russian Federation
Moscow
O. A. Litinskaya
Russian Federation
Moscow
M. S. Pokrovskaya
Russian Federation
Moscow
N. A. Imaeva
Russian Federation
Moscow
E. M. Filichkina
Russian Federation
Moscow
O. E. Ivlev
Russian Federation
Moscow
G. E. Svinin
Russian Federation
Moscow
L. I. Gomanova
Russian Federation
Moscow
Yu. V. Doludin
Russian Federation
Moscow
I. A. Efimova
Russian Federation
Moscow
A. L. Borisova
Russian Federation
Moscow
B. M. Nazarov
Russian Federation
Moscow
E. B. Yarovaya
Russian Federation
Moscow
T. V. Repkina
Russian Federation
Barnaul
T. O. Gonoshilova
Russian Federation
Barnaul
A. V. Kudryavtsev
Russian Federation
Arkhangelsk
N. I. Belova
Russian Federation
Arkhangelsk
L. L. Shagrov
Russian Federation
Arkhangelsk
M. A. Samotrueva
Russian Federation
Astrakhan
A. L. Yasenyavskaya
Russian Federation
Astrakhan
E. N. Chernysheva
Russian Federation
Astrakhan
S. V. Glukhovskaya
Russian Federation
Ekaterinburg
I. A. Levina
Russian Federation
Ekaterinburg
E. A. Shirshova
Russian Federation
Ekaterinburg
E. B. Dorzhieva
Russian Federation
Ulan-Ude
E. Z. Urbanova
Ulan-Ude
N. Yu. Borovkova
Russian Federation
Nizhny Novgorod
V. K. Kurashin
Russian Federation
Nizhny Novgorod
A. S. Tokareva
Russian Federation
Nizhny Novgorod
Yu. I. Ragino
Russian Federation
Novosibirsk
G. I. Simonova
Russian Federation
Novosibirsk
V. S. Shramko
Russian Federation
Novosibirsk
V. N. Nikulin
Russian Federation
Orenburg
O. R. Aslyamov
Russian Federation
Orenburg
G. V. Khokhlova
Russian Federation
Orenburg
A. V. Solovyova
Russian Federation
Tver
A. A. Rodionov
Russian Federation
Tver
O. V. Kryachkova
Russian Federation
Tver
Yu. Yu. Shamurova
Russian Federation
Chelyabinsk
I. V. Tantsyreva
Russian Federation
Chelyabinsk
I. N. Baryshnikova
Russian Federation
Chelyabinsk
M. G. Ataev
Russian Federation
Makhachkala
M. O. Radjabov
Russian Federation
Makhachkala
M. M. Isakhanova
Russian Federation
Makhachkala
M. A. Umetov
Russian Federation
Nalchik
L. V. Elgarova
Russian Federation
Nalchik
I. A. Khakuasheva
Russian Federation
Nalchik
E. I. Yamashkina
Russian Federation
Saransk
M. V. Esina
Russian Federation
Saransk
T. A. Kunyaeva
Russian Federation
Saransk
A. M. Nikitina
Russian Federation
Yakutsk
N. V. Savvina
Russian Federation
Yakutsk
Yu. E. Spiridonova
Russian Federation
Yakutsk
E. A. Naumova
Russian Federation
Cheboksary
A. A. Keskinov
Russian Federation
Moscow
V. S. Yudin
Russian Federation
Moscow
S. M. Yudin
Russian Federation
Moscow
A. V. Kontsevaya
Russian Federation
Moscow
S. A. Shalnova
Russian Federation
Moscow
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Supplementary files
What is already known about the subject?
- The results of numerous studies indicate that dyslipidemias make a significant contribution to atherosclerotic cardiovascular diseases and are associated with significant economic damage.
- Currently, there are no data on the prevalence of dyslipidemia in the Russian Federation, as well as their relationship with cardiovascular risk factors.
What might this study add?
- The prevalence of hypercholesterolemia in the Russian Federation in 2020-2022 was 58,8%, hypertriglyceridemia — 32,2%.
- Women are more informed about their cholesterol levels and are more likely to receive lipid-lowering therapy compared to men. Although the proportion of persons receiving lipid-lowering therapy increased with age, it accounted for only 7,6% of the general population.
- Hypertension, obesity, behavioral and social risk factors were significantly associated with dyslipidemia.
Review
For citations:
Drapkina O.M., Imaeva A.E., Kutsenko V.A., Kapustina A.V., Balanova Yu.A., Maksimov S.A., Muromtseva G.A., Kotova M.B., Karamnova N.S., Evstifeeva S.E., Litinskaya O.A., Pokrovskaya M.S., Imaeva N.A., Filichkina E.M., Ivlev O.E., Svinin G.E., Gomanova L.I., Doludin Yu.V., Efimova I.A., Borisova A.L., Nazarov B.M., Yarovaya E.B., Repkina T.V., Gonoshilova T.O., Kudryavtsev A.V., Belova N.I., Shagrov L.L., Samotrueva M.A., Yasenyavskaya A.L., Chernysheva E.N., Glukhovskaya S.V., Levina I.A., Shirshova E.A., Dorzhieva E.B., Urbanova E.Z., Borovkova N.Yu., Kurashin V.K., Tokareva A.S., Ragino Yu.I., Simonova G.I., Shramko V.S., Nikulin V.N., Aslyamov O.R., Khokhlova G.V., Solovyova A.V., Rodionov A.A., Kryachkova O.V., Shamurova Yu.Yu., Tantsyreva I.V., Baryshnikova I.N., Ataev M.G., Radjabov M.O., Isakhanova M.M., Umetov M.A., Elgarova L.V., Khakuasheva I.A., Yamashkina E.I., Esina M.V., Kunyaeva T.A., Nikitina A.M., Savvina N.V., Spiridonova Yu.E., Naumova E.A., Keskinov A.A., Yudin V.S., Yudin S.M., Kontsevaya A.V., Shalnova S.A. Dyslipidemia in the Russian Federation: population data, associations with risk factors. Cardiovascular Therapy and Prevention. 2023;22(8S):3791. (In Russ.) https://doi.org/10.15829/1728-8800-2023-3791. EDN: DGYJLA