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Transient ST-segment elevation in endovascular patent foramen ovale closure: a case report

https://doi.org/10.15829/1728-8800-2026-4541

EDN: FBFSNE

Abstract

Introduction. The complication rate of endovascular patent foramen ovale (PFO) closure is considered low. However, for most of complications, the rate has not been precisely determined. The most serious intraoperative complications include damage to the heart wall and vessels with bleeding, malpositioned occlude device, thromboembolism, and air embolism. Reports of severe and potentially fatal complications are rare, making their consideration and the determination of treatment strategies crucial.

Brief description. Patient K. aged 36 years had an ischemic stroke. Examination revealed a PFO with significant bypass grafting. Endovascular closure of the PFO was recommended to prevent recurrent ischemic events. During surgery, ST segment elevation was recorded in leads II and III. Selective coronary angiography revealed no contrast enhancement in the distal posterolateral and posterior descending arteries. Intracoronary nitroglycerin was administered, which restored flow in the artery. After the patient's condition stabilized, endovascular closure of the PFO was successfully completed, and an occluder was implanted.

Discussion. Possible causes of intraoperative ST segment elevation include gas embolism from air bubbles remaining in the delivery system after flushing, and mechanical irritation of the interatrial septum. Preventive measures include thorough flushing of the delivery system and selection of the occluder size based on heart anatomy.

About the Authors

A. S. Tereshchenko
Chazov National Medical Research Center of Cardiology
Russian Federation

Moscow



E. V. Merkulov
Chazov National Medical Research Center of Cardiology
Russian Federation

Moscow



A. S. Musaev
Chazov National Medical Research Center of Cardiology
Russian Federation

Moscow



G. V. Shchelkova
Chazov National Medical Research Center of Cardiology
Russian Federation

Moscow



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  • A patent foramen ovale can cause ischemic stroke.
  • Serious complications of endovascular closure of a pa­tent foramen ovale are rare, therefore their exact ra­te is unknown, and treatment strategies have not be­en developed.
  • A case demonstrates intraoperative ST segment ele­va­tion, which could have been caused by an air em­bo­lism.
  • As a preventative measure, the delivery system should be flushed until air bubbles disappear.

Review

For citations:


Tereshchenko A.S., Merkulov E.V., Musaev A.S., Shchelkova G.V. Transient ST-segment elevation in endovascular patent foramen ovale closure: a case report. Cardiovascular Therapy and Prevention. 2026;25(1):4541. (In Russ.) https://doi.org/10.15829/1728-8800-2026-4541. EDN: FBFSNE

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)