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Choosing optimal combination of neuro-humoral modulators in chronic heart failure: CHARM-Added study lessons

Abstract

The article is focused on choosing optimal doses and combinations of neuro-humoral modulators in systolic left ventricular dysfunction and heart failure. The results of CHARM-Added, Val-HeFT, RALES, and EPHESUS studies are analyzed, as well as their effect on modern recommendations on chronic heart failure diagnostics and treatment.

About the Author

Yu. M. Lopatin
Volgograd State Medical University, Volgograd Region Cardiology Center, Volgograd
Russian Federation


References

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Review

For citations:


Lopatin Yu.M. Choosing optimal combination of neuro-humoral modulators in chronic heart failure: CHARM-Added study lessons. Cardiovascular Therapy and Prevention. 2007;6(3):76-81. (In Russ.)

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)