Features of cerebral stroke course in patients with diabetes mellitus according to the REGION-M register

Aim. To assess the features of cerebral stroke course in patients with diabetes mellitus (DM) within the framework of the register of acute cerebrovascular event (ACVE) REGION-M.

Material and methods. From 2012 to 2017, the REGION-M register includes 900 patients who were admitted to one of the clinics in Moscow and had a stroke or transient ischemic attack.

Results. Patients with diabetes were older than patients without diabetes and impaired glucose tolerance (73,7+11,1 years vs 69,6±14,7 years (p<0,05)), more often had a history of coronary artery disease (74,2% vs 52,3%, respectively (p<0,05)) myocardial infarction (29,6% and 16,6%, respectively (p<0,05)). Arterial hypertension was found in most patients with stroke, but in patients with diabetes it was significantly more frequent (98,1% and 94,2%, respectively (p<0,05)). Obesity, anemia, kidney disease and chronic lung diseases were significantly more common in patients with diabetes than without it. The presence of diabetes was a factor that increased the risk of death by 2,1 times (odds ratio =2,1, 95% confidence interval, 1,5-3,0 (p<0,05)). When adjusting for other factors that had a negative effect on the hospital mortality (elderly age, coronary artery disease, atrial fibrillation and history of thrombosis), diabetes retained a negative prognostic effect.

Conclusion. The presence of diabetes significantly complicates the course of stroke and is an independent predictor of hospital mortality.

Region-M register working group: Akimova A.V., ArutyunovG. P., Belova E. N., Blagodatskikh S. V., Boytsov S. A., Vernokhaeva A. N., Viskov R. V., Voronina V. P., Gladilkina M. P., DeevA. D., Dmitrieva N. A., Drapkina O. M., Zagrebelnyi A. V., Kvitivadze G. K., Klyashtorny V. G., Kokareva I. V., KudryashovE. V., Kutishenko N. P., Lerman O. V., Lukina Yu. V., LukyanovM. M., Martsevich S. Yu., Matveeva A. D., Mat-skevich L. A., Mitichkin A. E., Nikitina G. I., Nikoshnova E. S., Ovse-pyan M. A., Okshina E. Yu., Palamarchuk V. N., Parsadanyan N. E., Porezanova M. V., Sementsov D. P., Stakhovskaya L. V., Stepina E. V., Stolboushkina E.A., Hapaeva M. A., Chernyshova M. I., ShamalovN. A.

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